Largest Chemical Companies in the US: Top 10 by Revenue 2025
The US chemical industry produces raw materials for plastics, pharmaceuticals, agriculture, and electronics. The ten largest chemical companies in the US by revenue for 2025 are Dow, LyondellBasell, ExxonMobil Chemical, Chevron Phillips Chemical, Huntsman Corporation, Eastman Chemical, Celanese, Westlake Corporation, Mosaic, and DuPont. These firms collectively generate hundreds of billions of dollars in annual sales and operate hundreds of manufacturing sites across the country.
How the Industry is Measured
The scale of these companies is tracked by organizations like the American Chemistry Council and trade publications such as Chemical & Engineering News. Their annual rankings typically exclude formulated products like pharmaceutical drugs and finished coatings, focusing instead on basic chemicals, intermediates, and specialty materials. The US market accounts for a significant share of global chemical sales, driven by abundant natural gas feedstocks and a large domestic customer base.
Dow
Dow is often the largest pure-play chemical company headquartered in the United States. It was formed in 2019 after the breakup of DowDuPont, which itself had been created by the merger of Dow Chemical and DuPont in 2017. Dow focuses on materials science, producing plastics (polyethylene, polyurethane), industrial intermediates, and specialty chemicals for packaging, infrastructure, and consumer applications. Its annual revenue typically exceeds $40 billion, and it operates major manufacturing complexes in Texas, Louisiana, and Michigan.
LyondellBasell
LyondellBasell is one of the world’s largest plastics, chemicals, and refining companies. It was formed in 2007 through the acquisition of Lyondell Chemical by Basell, and it is headquartered in Houston, Texas. The company is a leading producer of polypropylene and polyethylene, and it also makes propylene oxide, acetyls, and other intermediates. Annual revenue is generally in the range of $35-40 billion. LyondellBasell operates large integrated sites along the US Gulf Coast, as well as facilities in Europe and Asia.
ExxonMobil Chemical
ExxonMobil Chemical is a division of the integrated oil and gas giant ExxonMobil. It is one of the largest chemical companies by volume, producing basic chemicals like ethylene, propylene, and aromatics, as well as polyethylene and polypropylene. Its revenue is embedded within ExxonMobil’s overall results, but the chemical segment alone typically generates $25-30 billion in annual sales. The company benefits from access to low-cost feedstocks from its upstream operations, and it operates major petrochemical facilities in Texas, Louisiana, and Singapore.
Chevron Phillips Chemical
Chevron Phillips Chemical is a 50/50 joint venture between Chevron and Phillips 66. It is a major producer of olefins and polyolefins, including ethylene, propylene, polyethylene, and specialty chemicals like alpha olefins and styrenics. The company’s annual revenue is roughly $15-20 billion. Its largest manufacturing site is the Cedar Bayou facility in Baytown, Texas, and it also operates a major petrochemical complex in Qatar.
Huntsman Corporation
Huntsman Corporation is a global manufacturer of differentiated and specialty chemicals. It was founded in 1970 by Jon Huntsman Sr. and is headquartered in The Woodlands, Texas. The company operates in four main segments: polyurethanes, performance products, advanced materials, and textile effects. Huntsman’s annual revenue is typically in the range of $7-9 billion. It produces methylene diphenyl diisocyanate (MDI), amines, surfactants, and epoxy-based materials used in construction, automotive, and adhesives.
Eastman Chemical
Eastman Chemical was spun off from Eastman Kodak in 1994 and is an independent specialty materials company based in Kingsport, Tennessee. It produces a wide range of chemicals, fibers, and plastics, including cellulose acetate, copolyesters, and advanced intermediates for coatings and adhesives. Annual revenue is generally around $9-11 billion. Eastman operates a large integrated manufacturing site in Kingsport, as well as facilities in Texas, Europe, and Asia.
Celanese
Celanese is a global chemical and specialty materials company headquartered in Irving, Texas. It is a leading producer of acetyl products (acetic acid, vinyl acetate monomer) and engineered materials (polyoxymethylene, thermoplastic polyesters). Celanese’s annual revenue is typically in the range of $8-10 billion. The company operates large integrated chemical plants in Texas, as well as facilities in Europe, China, and Southeast Asia.
Westlake Corporation
Westlake Corporation is a vertically integrated manufacturer of basic chemicals, vinyls, polymers, and building products. It was founded in 1986 and is based in Houston, Texas. The company produces ethylene, polyethylene, polyvinyl chloride (PVC), and chlor-alkali products. Annual revenue is generally around $8-12 billion. Westlake operates manufacturing sites in the US, Canada, Germany, and China.
Mosaic
Mosaic is the largest producer of phosphate and potash fertilizers in the United States. It was formed in 2004 through the merger of IMC Global and Cargill’s crop nutrition business. Mosaic is headquartered in Tampa, Florida, and its annual revenue is typically in the range of $12-15 billion. The company mines phosphate rock in Florida and potash in Saskatchewan, Canada.
DuPont
DuPont is a specialty chemical and materials company that emerged from the 2019 breakup of DowDuPont. It focuses on electronics, transportation, construction, and industrial applications. DuPont’s product lines include Kevlar, Nomex, Tyvek, and Corian, as well as advanced polymers and photoresists for semiconductor manufacturing. Annual revenue is generally around $12-15 billion. The company is headquartered in Wilmington, Delaware, and operates research centers and manufacturing sites worldwide.
Specialty Chemicals vs. Commodity Chemicals
The ten largest US chemical companies are not all alike in what they produce. There is a basic distinction between commodity chemicals and specialty chemicals.
Commodity chemicals include ethylene, propylene, benzene, chlorine, and sulfuric acid. These are produced in very large volumes, sold on price, and their margins are closely tied to feedstock costs and global supply-demand balances. Dow, LyondellBasell, ExxonMobil Chemical, and Chevron Phillips Chemical are heavily weighted toward commodity petrochemicals.
Specialty chemicals are higher-value products sold based on performance rather than price. Examples include adhesives, sealants, electronic chemicals, water treatment polymers, and pharmaceutical intermediates. Huntsman, Eastman, Celanese, and DuPont have significant specialty chemical businesses. These products typically carry higher profit margins but smaller production volumes.
For instance, Eastman Chemical produces cellulose acetate tow, which is used in cigarette filters, and copolyesters for cosmetics packaging and medical devices. DuPont sells Kevlar fiber for ballistic protection and Nomex for fire-resistant clothing. These are not products that can be easily substituted by a cheaper competitor, which gives the manufacturers pricing power.
Regional Concentration Along the Gulf Coast
The majority of large-scale US chemical production is concentrated along the Gulf Coast of Texas and Louisiana. This region offers several advantages: proximity to natural gas and NGL feedstocks, access to deepwater ports for export, a skilled workforce, and a well-developed pipeline and storage infrastructure.
The Houston-Ship Channel area alone hosts dozens of petrochemical plants owned by Dow, LyondellBasell, ExxonMobil, Chevron Phillips, and others. The Louisiana Chemical Corridor, stretching from Baton Rouge to New Orleans, is another major cluster. Westlake Corporation operates a large vinyls complex in Geismar, Louisiana, while Mosaic has phosphate mining and processing operations in central Florida.
This geographic concentration creates both efficiencies and risks. A single hurricane or winter storm can disrupt production across multiple companies simultaneously. Companies have since invested in backup power systems and winterization measures to reduce vulnerability.
Key Takeaways
- The ten largest chemical companies in the US are Dow, LyondellBasell, ExxonMobil Chemical, Chevron Phillips Chemical, Huntsman Corporation, Eastman Chemical, Celanese, Westlake Corporation, Mosaic, and DuPont.
- These firms span basic petrochemicals, specialty materials, and agricultural nutrients, with combined annual revenues exceeding $200 billion.
- Many of the largest US chemical producers are based along the Gulf Coast, where low-cost natural gas feedstocks from shale formations provide a competitive advantage.
- Rankings are typically based on chemical sales excluding formulated products like pharmaceuticals and coatings, as tracked by industry groups and trade publications.
- Commodity chemical companies (Dow, LyondellBasell, ExxonMobil Chemical) compete on volume and cost, while specialty firms (Huntsman, Eastman, DuPont) focus on higher-margin performance products.
